Hi Mary Ann,

There is a potential interaction between Coumadin and Lovaza. Adding Lovaza, especially doses higher then 1 gram per day, may increase your INR, making you more prone to bleeding. This isn't to say that patients who take Coumadin can't take Lovaza. All this means is that you should make sure your doctor is aware that you are on both medications, and at least when you are starting Lovaza therapy, you should have your INR checked a little more frequently then you might be doing now. If your INR does increase when you start taking Lovaza, your doctor might just lower your Coumadin dose a little. That being said, I don't think you should be afraid of taking Lovaza with your Coumadin, just make sure your doctor is aware that you are taking both medications.

Thanks for your question!

Jill