Drug-eluting stents, such as the Endeavor stent, can reduce the likelihood of repeat artery narrowing (restenosis) after angioplasty to less than 10%. Anti-platelet therapy (such as plavix) is a key part of keeping the stent patent (open), and the combination of anti-platelet medication and aspirin is recommended with all stents.

Complex changes in the treated artery take place over several weeks to months after angioplasty and stent placement. These changes include inflammation and remodeling, and in part determine whether the vessel will stay open or become narrowed or blocked. Aspirin and an anti-platelet medication are typically given to all drug-eluting stent (DES) patients for at least 6-12 months after the procedure which covers the period of remodeling. Around 6 months after the procedure, the artery stabilizes, and the risk of re-stenosis decreases significantly.

Key questions include how long your wife has had this stent in place and what are your cardiologist’s recommendations. It is likely your wife should continue taking Plavix, though your doctor may want to increase the dose or try another anti-platelet drug. Removing the stent wouldn’t necessarily change this recommendation, as these medications are also used in patients with coronary artery disease who don’t have a stent.