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  Dawn,   Thanks for your question and I'm sorry to hear of your problems.  Coronary spasm is a known cause for acute coronary syndrome and also myocardial infarction (heart attack).  As you've pointed out, catheterization does not reveal any major blockages to explain the area of damage on an electrocardiogram.  Sometimes, during the catheterization, the doctor actually sees the artery spasm and narrowing.  It's this narrowing that causes the problems.  It creates a situation as if there were a blockage, with less blood flow to the heart muscle.  If blood flow slows enough, a clot could also form which can lead to a heart attack.     Fortunately there are several medications on the market that can be used for coronary spasm.  They  are in two broad classes.  One class is known as calcium channel blockers, available in different formulations and different doses.  These drugs cause blood vessels to dilate and deliver more blood.  Used on a regular basis, they can help prevent the spasm from occurring.     The other class is nitrates, which also cause blood vessels to dilate.  They are available in many forms: pills; patches; pastes; and, small tabs to dissolve under the tongue.    Though nitrates and Calcium Channel blockers are commonly used to treat heart disease, the Calcium Channel blockers are also used to treat high blood pressure.  Therefore, in a situation such as yours, your doctors are trying to control the spasm, and unfortunately you're experiencing the side effects, which probably include low blood pressure (which can be caused by both classes of drugs).  With trial and error, and fine adjustment of doses, you should be stabilized at some point.  Your body should adjust to most of the side effects.  And hopefully, you will then be leading a normal life again.    Have patience.  It sounds like your doctors are on the right track.  Don't hesitate to discuss your feelings and concerns with your doctors who will provide explanations and reassurance.   Best wishes.   Martin Cane, M.D.
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