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Bone graft material is used whenever there's a need for extra bone to support a fracture site or defect in the bone. It's easily available (taken from the patient's pelvic bone) and inexpensive. And it is bone inductive (fosters bone growth) to provide structural support to the damaged area. The downside is that the graft site can be painful for a very long time. In some cases, infection can delay recovery. Patients often report difficulty walking due to the pain. And the combination of pain and impaired walking result in loss of function. To help patients avoid the major and minor complications of bone graft, scientists are exploring the use of bone substitutes. One of those bone substitutes ( alpha-BSM ) is the subject of this study. Patients with an acute fracture of the tibial plateau were the subject of this multicenter study. Twelve study sites from around the North American continent were involved. The tibial plateau is the flat top of the upper portion of the tibia (lower leg bone...
Transplant - bone marrow; Stem cell transplant; Hematopoietic stem cell transplant; Reduced intensity, nonmyeloablative transplant; Mini transplant; Allogenic bone marrow transplant; Autologous bone marrow transplant; Umbilical cord blood transplant
A bone marrow transplant may cause the following symptoms:
Drop in blood pressure
Shortness of breath
Funny taste in the mouth
Possible complications of a bone marrow transplant depend on many things, including:
The disease you are being treated for
If you had chemotherapy or radiation before the bone marrow transplant
Your overall health
How good of a match your donor was
The type of bone marrow transplant you received (autologous, allogeneic, or umbilical cord blood)
Complications can include:
Infections, which can be very serious
Alternative Names Aches and pains in bones; Pain - bones References Choi L. Overuse injuries. In: DeLee JC, Drez D Jr, Miller MD, eds. DeLee and Drezs Orthopaedic Sports Medicine. 3rd ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 14. Lorenzo JA, Canalis E, Raisz LG. Metabolic bone disease. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology . 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 28.
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