Friday, October 24, 2014

Tuesday, November 18, 2008 maria, Community Member, asks

Q: can i take ibuprofen and hydrocodone at the same time?

Can I take ibuprofen and hydrocodone at the same time? How about on the same day if the effect of hydrocodone does not last for more than four hours? If so, can I take 800 mg of ibuprofen?  Thanks for any advice.

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Answers (2)
mary, Community Member
11/20/08 8:03am

You know, the best person to answer medication questions is your local Pharmacist. That's exactly what they go to school for and they know more then a reg. doctor. Hydrocodone contains acetaminophen (tylenol) and usually acetaminophen and ibuprofen should not be taken at the same time but can be spread out by at least 2-3 hours. Call your pharmacist to confirm.

Amy Tudor, Editor
8/ 1/14 12:51pm

Hi Maria -


I know this is a very old question, but I did want someone from our staff to answer it for you!


According to this article from the Mayo Clinic, these two drugs are sometimes prescribed together for a short period of time to relieve pain. The recommendation is that it not be done for more than 10 days, however, though as a layperson, I'm not sure what the reason for the short duration could be. You should always talk to your pharmacist or doctor about drug interactions, since he or she will know more about your medical history and the other meds you're taking.


Here are some links to articles on pain management on our site.  I hope this is helpful!


Let’s Talk Pain Meds

What You Didn’t Know About Pain Meds

Give Your Medicine Chest a Check-Up


Be well!


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By maria, Community Member— Last Modified: 08/01/14, First Published: 11/18/08