Hi Carolyn,   First, always discuss supplements you take or are considering with your MD.    There are possible drug interactions with fish oil.  Blood-thinning medications - Fish oil may increase the action of blood-thinners, such as aspirin and warfarin.  The National Institute of Health states that supplementing fish oil (omega-3 fatty acids) over 3 grams per day may increase bleeding risk.  Fish oil appears to decrease platelet aggregation (clotting), resulting in increased bleeding (nosebleeds, blood in the urine, strokes).   If you take blood thinners and fish oil, you should be monitored by your MD. Cyclosporine - Fish oil may slightly reduce the side effects (used in transplant patients). Cholesterol Lowering Medications ("statins") - Fish oil as part of a heart healthy diet may improve the effectiveness of statins. Non-steroidal Anti-Inflammatory Drugs (NSAIDS) - Supplementing fish oil may decrease ulcer risk when taking NSAIDS, such as aspirin or ibuprofen. Etretinate and Topical Steroids - Fish oils may aid psoriasis treatment.  Again, consult with your MD before using a supplement.   All the best,   Lisa Nelson, RD, LN Lower Cholesterol, Control Blood Pressure, Lose Weight