You are asking about the potential for "regression," the process by which heart blockages can be made to partially get better. There is now evidence that this is possible in some people through a combination of lifestyle changes, exercise, diet, and when needed, cholesterol lowering. However, in general the major issue is not making heart blockages go away, rather just making sure that they don't get worse or cause another heart attack. We now have tremendous evidence that future heart attacks can be prevented, especially by aggressive treatment to lower cholesterol.