Coronary Artery Disease - Risk Factors

  • Angina pain or discomfort is typically described by patients as fullness or tingling, squeezing, pressure, heavy, suffocating, or griplike. It is rarely described as stabbing or burning. Changing one's position or breathing in and out does not affect the pain.
  • A typical angina attack lasts minutes. If it is more fleeting or lasts for hours, it is probably not angina.
  • Pain is usually in the chest under the breast bone. It often radiates to the neck, jaw, or left shoulder and arm. Less commonly, patients report symptoms that radiate to the right arm or back, or even to the upper abdomen.
  • Women are particularly likely to experience atypical symptoms that often involve discomfort in the abdomen instead of the chest.
  • Stable angina is usually relieved by rest or by taking nitroglycerin under the tongue.

Other symptoms that may indicate angina or accompany the pain or pressure in the chest include:

  • Shortness of breath
  • Nausea, vomiting, and cold sweats
  • A feeling of indigestion or heartburn
  • Unexplained fatigue after activity (more common in women)
  • Dizziness or lightheadedness
  • Palpitations

Unstable Angina and Acute Coronary Syndrome

Unstable angina is a much more serious situation and is often an intermediate stage between stable angina and a heart attack, in which an artery leading to the heart (a coronary artery) becomes completely blocked. A patient is usually diagnosed with unstable angina under one or more of the following conditions:

  • Pain awakens a patient or occurs during rest.
  • A patient who has never experienced angina has severe or moderate pain during mild exertion (walking two level blocks or climbing one flight of stairs).
  • Stable angina has progressed in severity and frequency within a 2-month period, and medications are less effective in relieving its pain.
  • Fainting episode.

Unstable angina is usually discussed as part of a condition called acute coronary syndrome (ACS). ACS also includes people with a condition called NSTEMI (non ST-segment elevation myocardial infarction) -- also referred to as non-Q wave heart attack. With NSTEMI, blood tests suggest a developing heart attack. These conditions are less severe than heart attacks but may develop into full-blown attacks without aggressive treatment. [For more information, see In-Depth Report #12: Heart attack and acute coronary syndrome.]

Other Types of Angina

Prinzmetal's Angina. A third type of angina, called variant or Prinzmetal's angina, is caused by a spasm of a coronary artery. It almost always occurs when the patient is at rest. Irregular heartbeats are common, but the pain is generally relieved promptly with standard treatment.

Silent Ischemia. Some people with severe coronary artery disease do not have angina pain. This condition is known as silent ischemia, which may occur when the brain abnormally processes heart pain. This is a dangerous condition because patients have no warning signs of heart disease. Some studies suggest that people with silent ischemia have higher complication and mortality rates than those with angina pain. (Angina pain may actually protect the heart by conditioning it before a heart attack.)

Other Causes of Chest Pain or Discomfort

Chest pain is a very common symptom in the emergency room, but heart problems account for only 10 - 33% of all episodes. There are many other causes of chest pain or discomfort including injured muscles, arthritis, heartburn, and asthma.



Review Date: 05/05/2011
Reviewed By: Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)

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