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Maria m, Thanks for your question. I have been unable to find any listing that Cymbalta can cause High Blood Pressure. This does not mean that it's not possible. I've always felt that any medication can cause any side effect in any individual. Certainly the stress at work and home can be a factor. I suggest you contact your physician for an appointment to have your pressure checked and to discuss whether the cymbalta may be a factor in your blood pressure changes. Best wishes. Martin Cane, M.D.

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