Bryan,

My heart goes out to you and your wife. To help her you will have to play detective gathering clues and doing research.

First thing take all her medications and do some research online about side effects. I like to go to www.drugs.com because the have a link to a more detailed/advance listing of side effects. Next look for interactions with everything she takes, all the medications, OTR medications, vitamins and supplements.This is where I would suspect the first problem. www.iguard is a good website to use to check interactions.

Next talk about each situation and she if there is some linking detail, was she eating, was late in the day, was it early, did she miss a medication or did take one late or early? What time of the month do these attack happen? Could this be hormonally related? Estrogen or the lack of it can make a woman pretty crazy. I can say that having been there. Has anything changed right before or since the attacks started. It could be sleeping or not, her hair changed or her skin was different. Every detail is important. What is going on at her job? Increase stress, a major project or a new promotion?

Has your wife had a recent physical or labwork? If so, were things in the normal/expected ranges? You want to rule out anything new conditions or something being out control/target ranges.

I just did some research and her symptoms sound like some of classic symptoms of hyperthyroidism? What I read is this comes on slowly and often appears as nervousness. Ha sher doctor check her thyroid? Does she have a family history of any kind of thyroid problems? She might need to call Mom and ask these questions. I found out off handly that mother has hypothyroidism. Her doctor told her to have her sister get tested because they probably were having problems too. I keep this mind and have my levels checked yearly.

I hope I helped in some way and I hope you find some answers. Please post a response so I know. I will be praying for all of you during this difficult time.

Reta