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Hi Latwion33,   I've have looked into Alli and according to the manufacturer and studies Alli is safe to take with high blood pressure; however, I recommend being cautious. If I was in your position I would start with the diet and exercise routine. If you make a serious committment, make the necessary changes, and after several weeks are not seeing results, then I'd consult your physician about adding Alli.   All the best, Lisa Nelson RD Top 5 Key Strategies to Lose Weight Permanently  
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