Went on several different blood pressure pills. Developed rash and itching on area around calves/shin and also arms from wrists to elbows. Had feeling of something crawling under skin at times. Whenever I exercised, symptoms got relieved(walked 1 mile 2x's per day at 30 min/mile and rode exercise bike 60rpm for 20min) Symptoms would go away within 10-15min.  Take blood pressure pills, symptoms would come back right away. Stopped blood pressure pills and kept up exercise and took about 2months for symptoms to go away completely. Needless to say doctor is not happy but I feel better. Talked with someone in epidemiology, who said that rash is likely caused by subacute infections in blood due to pooling in legs and arms; doctors don't treat, more worrried about high blood pressure. Unfortunately, subacutes become acutes in time and with low blood pressure, antibiotics tend to be overdosed as well since circulation is poor. He says that he tired of talking to docs about dangers of not enough blood pressure in older patients with poor blood vessel flow. Worrying about heart is fine, but need enough pressure in blood vessels to get oxygen to cells and move out toxins and bacteria. You must make your own decision. Caught between rock and hard place-lower blood pressure helps heart but may prevent enough circulation to cells and blood pools in arms and legs. I decided to keep up exercise long term, stop blood pressure pills(even a quarter dose causes the blood flow to go too low) and hope that by reducing weight and exercise I can get healthy enought to not need pills. I am 70 years old.