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Wednesday, December, 02, 2009
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can anti inflammatory medication be taken with Accupril

Lynn Jenkins
12/17/08
Lynn Jenkins
Topics:High Blood Pressure Medication

I often take Tilcotil (anti inflammatory Med) for historical sports injuries. I have heard that these drugs do not interact well with blood pressure medication. Can you please clarify if this is correct or not.

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Answers (1)
Martin Cane, M.D.
Thursday, December 18, 2008

JILL IBARRA,

 

Thanks for your question.

 

Accupril is a blood pressure medication known as an ACE inhibitor.  It works by blocking an enzyme responsible for the production of Angiotensin II, a powerful hormone that causes blood vessels to contrict (narrow) as well as cause water and salt retention in the kidney.  These actions are blocked by the lisinopril which results in a lower blood pressure.  Accupril has a low side effect profile and can be combined with many drugs without problems.

 

Tilcotil (tenoxicam) is an anti-inflammatory (NSAID) medication used for various conditions for the relief of pain and inflammation. 

 

The use of non-steroidal anti-inflammatory  drugs (ANSAIDs) including Cox 2 inhibitors, may diminish the anti-hypertensive effect of the accupril.  Drugs like Tylenol (acetominophen) are not a problem. 

 

The safest thing to do is check with your physician or pharmacist about potential interactions. 

 

Best wishes.

 

Martin Cane, M.D.

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