Melatonin is a naturally occurring hormone in the body that is produced by the pineal gland. It has been well known for its role in the sleep cycle but has more recently been shown to function as an antioxidant and as a player in proper immune system functioning.
There is currently a Phase II clinical trial recruiting subjects with ulcerative colitis to test the efficacy of melatonin supplements in lessening symptoms of the disease ( 1 ). It is important because previous research in animals has noted that melatonin plays a significant role in the health of the GI tract. With regard to inflammation and GI bleeding one rodent study found that the melatonin resolved the issue in all cases ( 2 ).
The additional benefit to something like melatonin is the relatively low risk of side effects as compared with the other treatments for UC. Some of the side effects that can be experienced with melatonin are: dizziness, daytime sleepiness, headache, abdominal pain, vivid dreams or confu...
Melatonin is a sleep hormone, produced by the pineal gland seated deep inside the brain,
as well as other parts of the body, such as the gastrointestinal tract. For
years, melatonin has been recognized as a regulator of circadian rhythms ,
the natural cycle of sleep and wakefulness that has allowed humans to inhabit
the earth in phase with the cycles of night and day.
of the retina (in the back of the eye) to light suppresses release of melatonin
into the blood; darkness triggers release. Nighttime levels of melatonin surge
10-fold higher compared to that of daytime levels. In the modern world,
authorities have proposed that lack of melatonin may be a by-product of
interior lighting that extends into the evening hours. Evidence has emerged
suggesting that lack of melatonin may contribute to increased potential for
of this fascinating hormone has shown potential benefit through a variety of
favorable effects on cardiovascular paramet...
In some countries with universal or nationalized health care, a joint replacement is considered an elective procedure. That means the person chooses to have the operation but it's not an emergency procedure. So despite pain and loss of motion or function, that individual must wait in a queue (line) until the resources are available to them. This could take weeks to months. In the meantime, they are advised to stay active. What's the best way to do that? Should patients exercise on land or in a pool? Is one better than the other? That's what the researchers involved in this study wanted to find out. Physical therapists from down under (Australia) compared patients with hip or knee osteoarthritis exercising either on land (group one) or in a pool-based program (group two) while waiting for surgery. The patients were randomized (randomly placed) into one group or the other. They were all found to be medically fit and able to exercise. Both groups engaged in their respective exercise (land-...
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