My mother has hypertension and has been on BP meds for years. The last few months she has had several "episondes" where she will be winding down for the night and she will have a BP spike. Twice she has been hospitalized and they have ran a battery or tests and come up with nothing. Her heart is in good shape, but I am afraid that if this pattern continues she will end up having a stroke. The latest episode landed her in the hospital for 3 days and the doctor ended up checking her for adrenal cancer. He finally came back and said that it was linked to her anxiety, so he tripled her medication and added Paxil. She couldn't stand the BP so high and the Paxil made her worse, so she is no longer on Paxil and he lowered her from 360mg to 120mg. I don't buy that it is her anxiety because if it were she would have these episodeds at any time of the day. What would cause her BP to spike at night?