Aldactone Oral

Aldactone Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

• eplerenone

If you are currently using the medication listed above, tell your doctor or pharmacist before starting spironolactone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• corticosteroids (e.g., prednisone)
• certain hormones (ACTH)
• digoxin
• lithium
• mitotane
• nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, indomethacin)
• other diuretics that increase potassium (e.g., amiloride, triamterene)

Other medications besides this medication which may increase your potassium levels include cyclosporine, tacrolimus, potassium supplements, ACE inhibitors (e.g., captopril, lisinopril) or ARBs (e.g., losartan, candesartan). Follow your doctor's instructions carefully and continue medications for your condition as directed. Limit foods high in potassium such as bananas, tomatoes, potatoes, low-salt milk, and salt substitutes. Consult your doctor or pharmacist for more details, including diet recommendations. It is important to keep all medical and laboratory appointments so your doctor can monitor your potassium levels regularly.

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or worsen swelling (edema). Some nonprescription medicines that contains aspirin may decrease the effects of spironolactone. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually these dosages are 81-325 milligrams per day) should be continued. Consult your doctor or pharmacist for more details.

This medication can affect the results of certain lab tests (e.g., digoxin or cortisol levels). Make sure laboratory personnel and your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.