INSPRA Oral

INSPRA Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

• certain azole antifungals (ketoconazole, itraconazole)
• certain macrolide antibiotics (clarithromycin, troleandomycin)
• nefazodone
• potassium supplements
• potassium-sparing diuretics (e.g., amiloride, spironolactone, triamterene)
• certain protease inhibitors (nelfinavir, ritonavir)

If you are currently using any of these medications, tell your doctor or pharmacist before starting eplerenone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• ACE inhibitors (e.g., captopril, enalapril)
• angiotensin II blockers (e.g., losartan, valsartan)
• other azole antifungals (e.g., fluconazole)
• lithium
• other macrolide antibiotics (e.g., erythromycin)
• other protease inhibitors (e.g., saquinavir)
• nonsteroidal anti-inflammatory drugs (e.g., NSAIDs like ibuprofen, indomethacin, naproxen)
• St. John's wort
• verapamil

Consult your doctor or pharmacist before using potassium-containing products (salt substitutes) or eating large amounts of potassium-containing foods (e.g., bananas).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.