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Friday, November 13, 2009
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Dyazide Oral

Drug Interactions


Generic Name: TRIAMTERENE/HYDROCHLOROTHIAZIDE - ORAL
Pronounced: (HYE-droe-KLOR-oh-THYE-a-zide/try-AM-ter-een)

Dyazide Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

See also the How to Use section.

This drug should not be used with the following medications because very serious interactions may occur:

  • dofetilide
  • eplerenone
  • other potassium-sparing diuretics (e.g., spironolactone, amiloride)
  • tacrolimus


If you are currently using any of these medications, tell your doctor or pharmacist before starting hydrochlorothiazide/triamterene.

Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause very serious side effects.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • cisapride
  • ACE inhibitors (e.g., captopril, lisinopril)
  • angiotensin receptor blockers (e.g., losartan, valsartan)
  • cholestyramine
  • colestipol
  • diazoxide
  • digoxin
  • lithium
  • nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, indomethacin)


Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist about the safe use of those products.

This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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