Wednesday, October 15, 2008

BiDil Oral

Precautions and Side Effects


Generic Name: ISOSORBIDE DINITRATE/HYDRALAZINE - ORAL
Pronounced: (eye-so-SORE-bide dye-NYE-trate/hi-DRAL-uh-zeen)

BiDil Oral Side Effects

Table of Contents

Dizziness, lightheadedness, headache, loss of appetite, nausea, vomiting, diarrhea, constipation, flushing, eye watering/redness/itchiness, or stuffy nose may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Headache usually means that the medication is working. Treat headaches with an over-the-counter pain reliever (e.g., acetaminophen) as directed by your doctor. If the headaches continue or become severe, tell your doctor.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • fast/irregular heartbeat
  • unusual/severe/persistent dizziness
  • fainting
  • shaking (tremor)
  • paleness
  • sweating
  • blurred vision
  • dry mouth
  • muscle cramps
  • mental/mood changes (e.g., depression, unusual behavior, confusion)
  • trouble urinating
  • severe vomiting
  • severe constipation
  • decreased sexual ability


This medication may infrequently cause nerve problems. Tell your doctor promptly if you experience numbness or tingling. Your doctor may recommend a vitamin B6 supplement (pyridoxine).

This medication may infrequently cause a serious immune system problem (systemic lupus erythematosus), which may occur with or without a certain severe kidney problem (glomerulonephritis). Tell your doctor immediately if you experience any of these unlikely but serious side effects:

  • unusual tiredness
  • joint/muscle aches
  • unusual fever
  • butterfly-shaped facial rash
  • swollen glands
  • bloody/pink urine
  • swelling of the feet/ankles


Your doctor may need to order special tests if you experience these symptoms. Keep all laboratory and medical appointments.

Tell your doctor immediately if any of these rare but very serious side effects occur:

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