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Propranolol Oral Medication Interactions


IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.

Generic Name: PROPRANOLOL S.R. - ORAL
Pronounced: (pro-PRAN-oh-lol)

Propranolol Oral Interactions

See also How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medication because very serious interactions may occur:

  • thioridazine

If you are currently using this medication, tell your doctor or pharmacist before starting propranolol.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • alpha blockers (e.g., prazosin)
  • aluminum hydroxide
  • anticholinergics (e.g., atropine, scopolamine)
  • calcium channel blockers (e.g., diltiazem, verapamil)
  • chlorpromazine
  • diazepam
  • drugs to treat diabetes (e.g., insulin, sulfonylureas such as glipizide/glyburide)
  • other drugs to treat high blood pressure (e.g., clonidine, hydralazine, methyldopa, reserpine)
  • epinephrine
  • haloperidol
  • other heart medications (e.g., amiodarone, digoxin, disopyramide, propafenone, quinidine)
  • MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine)
  • mefloquine
  • rizatriptan
  • theophylline
  • thyroid hormones (e.g., levothyroxine)
  • tricyclic antidepressants (e.g., amitriptyline)
  • warfarin
  • drugs affecting liver enzymes that remove propranolol from your body (such as cimetidine, St. John's wort, certain SSRI antidepressants including fluoxetine/paroxetine/fluvoxamine, HIV protease inhibitors including ritonavir, rifamycins including rifabutin, certain anti-seizure medicines including carbamazepine)

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about using those products safely.

This medication may interfere with certain laboratory tests (including glaucoma screening test, cardiovascular stress testing using arbutamine), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised September 2011 Copyright(c) 2011 First DataBank, Inc.