Welcome to the forum, BunnyMomma.   I'm sorry that you've been feeling so "down" lately, but I am glad that swimgirl was able to dive right in with some heartfelt, practical advice. (Did I make you laugh? Smile, maybe?)   I wonder how much your nutritional status is affecting your emotional state, as well. Are you taking a good multi vitamin, with extra vitamin D and calcium? Forvia brand vitamins, especially made to be bio-available for people with IBD, is an excellent one. You can only buy it on line, directly from the company's website (www.forvia.com).   You mentioned that you know that your B 12 level is low. A deficiency of vitamin B 12 is often seen in Crohn's disease of the small bowel, and in some other malabsorption problems related to small bowel disease.   Lack of folic acid and/or vitamin B 12 is often a cause of a type of anemia known as macrocytic anemia. It is the anemia which causes fatigue--not the other way around!   Be well- Hope