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Imodium A-D Oral

Drug Interactions


Generic Name: LOPERAMIDE - ORAL
Pronounced: (low-PAIR-uh-mide)

Imodium A-D Oral Interactions

If you are taking this medication under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because a very serious interaction may occur:

  • pramlintide


If you are currently using the medication listed above, tell your doctor or pharmacist before starting loperamide.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • recent/current antibiotic use
  • drugs that can cause constipation (e.g., anticholinergics such as belladonna/scopolamine/benztropine, antispasmodics such as glycopyrrolate/oxybutynin, potent narcotic pain medicines such as morphine, certain antihistamines such as diphenhydramine, tricyclic antidepressants such as amitriptyline)
  • cholestyramine
  • quinidine
  • ritonavir
  • saquinavir


This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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