Wednesday, February 15, 2012
Tuesday, July 01, 2008 kurbkrawler00 asks

Q: I just finished my antibiotic therapy which was Macrobid 100 mg bid..i noticed a darker color of my

urine..and developed a nose bleed..this drug made me feel better almost over night. I also gained some control of my urgencys. I could hold it without the sudden urge. I have been diagnosed previously with cancer of prostate and bladder. I have a upcoming biopsy in July...I was supprised to be told i mayNOT have cancer afterall...does this happen alot ????also should i call my urologist and tell him I may need a refill onmy Med,Macrobid ? My urine has become cloudy again,after only 2 days..

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7/ 4/08 9:04am

Macrobid can darken your urine. The dark color is not indicative of any problems. From my personal experience (and everyone is different) for me this indicates I'm not taking it properly. Macrobid works best when taken with a meal. I have read studies that indicate its bioavailability increases by about 40%. If I take it with food (like I'm supposed to) it does not darken my urine. If I take it on an empty stomach, my urine is more likely to be dark. Also, don't take it within a few hours of taking anything for heartburn. Some heartburn meds (particularly those containing magnesium trisilicate) reduce the effectiveness.

 

See the following on Macrobid:

 

http://www.rxlist.com/cgi/generic/nitro25m_cp.htm

 

http://www.truestarhealth.com/Notes/1445008.htm

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