Enablex Oral

Enablex Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

• pramlintide

If you are currently using the medication listed above, tell your doctor or pharmacist before starting darifenacin.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• potassium tablets/capsules
• other drugs that can cause dry mouth and constipation (e.g., anticholinergic medications such as atropine, antihistamines including diphenhydramine and scopolamine, other antispasmodics including dicyclomine, belladonna alkaloids)
• drugs affecting liver enzymes that remove darifenacin from your body (such as azole antifungals including itraconazole; macrolide antibiotics including clarithromycin; ritonavir; nelfinavir; nefazodone; rifamycins including rifabutin; St. John's wort; certain anti-seizure medicines including carbamazepine)

This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include:

• flecainide
• thioridazine
• tricyclic antidepressants (e.g., amitriptyline, imipramine)

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.