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Wednesday, November 25, 2009
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Sudafed Oral

Drug Interactions


Generic Name: PSEUDOEPHEDRINE - ORAL
Pronounced: (sue-doh-eff-ED-rin)

Sudafed Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine, rasagiline)


Avoid taking MAO inhibitors within 2 weeks before, during, and after treatment with pseudoephedrine. In some cases a serious, possibly fatal drug interaction may occur.

If you are currently using any of these medications, tell your doctor or pharmacist before starting this product.

Before using pseudoephedrine, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • other decongestants (taken by mouth or sprayed into the nose)
  • products containing caffeine


Pseudoephedrine may decrease the effectiveness of some blood pressure medications (e.g., beta blockers, calcium channel blockers, reserpine, guanethidine, methyldopa).

Pseudoephedrine may worsen the serious side effects of some medications used for migraine headaches (e.g., sumatriptan, naratriptan, zolmitriptan, ergotamine). Consult your pharmacist or doctor for more details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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