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Wednesday, November 25, 2009
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Interstitial cystitis

Female urinary tract
Female urinary tract
Male urinary tract
Male urinary tract
Alternative Names

Cystitis - interstitial; IC


Treatment

There is no cure for IC, and there are no standard or consistently effective treatments. Results vary from person to person. As long as the cause is unknown, treatment is based on trial and error until you find relief.

Elmiron is the only medication taken by mouth that is specifically approved for treating IC. This medicine coats the bladder like Pepto-Bismol coats the stomach.

Other medicines may include:

  • Opioid painkillers for severe pain
  • Tricyclic antidepressants such as Elavil (amitriptyline) to relieve pain and urinary frequency
  • Vistaril (hydroxyzine pamoate), an antihistamine that causes sedation, helps reduce urinary frequency

Other therapies include:

  • Bladder hydrodistention (filling bladder with fluid)
  • Bladder training (using relaxation techniques to train the bladder to go only at specific times)
  • Instilled medications - medicines are placed directly into the bladder. Medicines that are given this way include dimethyl sulfoxide (DMS), heparin, Clorpactin, lidocaine, doxorubicin, or bacillus Calmette-Guerin (BCG) vaccine.
  • Physical therapy and biofeedback (may help relieve pelvic floor muscle spasms)
  • Surgery, ranging from cystoscopic manipulation to bladder removal (cystectomy)

Diet modification

Some patients find that changes in their diet can help control symptoms. The idea is to avoid foods and beverages that can cause bladder irritation. Below are some of the foods that the Interstitial Cystitis Association says may cause bladder irritation.

  • Aged cheeses
  • Alcohol
  • Artificial sweeteners
  • Chocolate
  • Citrus juices
  • Coffee
  • Cranberry juice (Note: Although cranberry juice is often recommended for urinary tract infections, it can make IC symptoms worse.)
  • Fava and lima beans
  • Meats that are cured, processed, smoked, canned, aged, or that contain nitrites
  • Most fruits except blueberries, honeydew melon, and pears
  • Nuts except almonds, cashews, and pine nuts
  • Onions
  • Rye bread
  • Seasonings that contain MSG
  • Sour cream
  • Sourdough bread
  • Soy
  • Tea
  • Tofu
  • Tomatoes
  • Yogurt
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Review Date: 05/22/2008
Reviewed By: Scott M. Gilbert, MD, Department of Urology, Columbia-Presbyterian Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).
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