Before taking this medication, tell your doctor if you are allergic to dipyridamole; or to aspirin; or to other salicylates (such as choline salicylate); or to NSAIDs (such as ibuprofen, naproxen); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
- aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs)
- bleeding problems (such as hemophilia, vitamin K deficiency, low platelets)
- low blood pressure (hypotension)
- heart problems (such as angina, heart attack)
- stomach problems (such as ulcers, heartburn)
- kidney disease
- liver disease
- a certain muscle problem (myasthenia gravis)
- growths in the nose (nasal polyps)
- bleeding in the brain
This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may instruct you to stop aspirin/dipyridamole 7-10 days before surgery. Do not stop taking this medication without first talking with the doctor who prescribed it.
The amount of aspirin in this medication may not be enough to prevent heart attack. If you need aspirin to prevent heart attack, consult your doctor or pharmacist for more information.
This drug contains aspirin. Children and teenagers should not take aspirin if they have chickenpox, flu, or any undiagnosed illness or if they have recently received a vaccine. In these cases, taking aspirin increases the risk of Reye's syndrome, a rare but serious illness.
Older adults may be more sensitive to the side effects of this drug such as bleeding.
Aspirin is not recommended for use during pregnancy. This medication should be used only when clearly needed during the first 6 months of pregnancy. Do not use this medication during the last 3 months of pregnancy because of possible harm to the unborn baby or problems during delivery. Discuss the risks and benefits with your doctor.
Aspirin and dipyridamole passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Headache, nausea, and heartburn may occur. Talk with your doctor if you have a severe headache when you first start taking this medication. Your doctor may change your dose for the first week to lessen headache. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur:
- easy bleeding/bruising
- uncontrolled bleeding from gums or nose
- fast/slow/irregular heartbeat
- dark urine
- yellowing eyes/skin
This drug may infrequently cause serious bleeding (especially from the stomach or intestines). If you notice any of the following rare but serious side effects, stop taking this medication and consult your doctor or pharmacist immediately:
- bloody/black/tarry stools
- pale/bluish skin color
- unusual weakness
- vomit with blood or that looks like coffee grounds
- persistent stomach/abdominal pain
Get medical help right away if any of these rare but serious side effects occur:
- symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating)
- signs of bleeding in the brain or stroke (such as weakness on one side of the body, slurred speech, sudden vision changes, confusion)
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
- severe rash
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.