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Azathioprine Oral Uses and How to Use


IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.

Table of Contents

Generic Name: AZATHIOPRINE - ORAL
Pronounced: (ay-za-THYE-oh-preen)

Azathioprine Oral Uses

Azathioprine is used with other medications to prevent rejection of a kidney transplant. It works by weakening your body's defense system (immune system) to help your body accept the new kidney as if it were your own. This medication belongs to a class of drugs known as immunosuppressants.

Azathioprine is also used to treat patients with severe rheumatoid arthritis who have not responded to other medications (e.g., nonsteroidal anti-inflammatory drugs/NSAIDs such as ibuprofen). Rheumatoid arthritis is thought to be caused by the immune system attacking the joints. Early treatment of rheumatoid arthritis with more aggressive therapy such as azathioprine helps to reduce further joint damage and to preserve joint function.

Talk to the doctor about the risks and benefits of azathioprine, especially when used in children and young adults.

How To Use Azathioprine Oral

Take this medication by mouth, usually once or twice daily as directed by your doctor. Azathioprine should be taken with food to reduce stomach upset. Dosage is based on your medical condition, weight, and response to therapy. For the treatment of rheumatoid arthritis, the manufacturer recommends that you do not take more than 2.5 milligrams per kilogram per day.

Do not increase your dose or take this medication more often without your doctor's approval. Your condition will not improve any faster and the risk of serious side effects may be increased. Also do not stop taking this medication without your doctor's approval.

Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) each day.

For arthritis, it may take up to 2 months of continued use to notice relief of symptoms. Inform your doctor if your condition does not improve after 3 months of treatment.

Since this drug can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle or break the tablets of this medication.


CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised July 2011 Copyright(c) 2011 First DataBank, Inc.