IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.
Table of Contents
- Uses and How to Use
- Precautions and Side Effects
- Medication Interactions
- Dosage and Storage
- Medication Images
Pronounced: (KOL-a-JEN-ase klos-TRID-ee-um HIS-toe-LIT-ik-um)
Collagenase Clostridium Hist. Inj Uses
This medication is used to treat Dupuytren's contracture. Dupuytren's contracture is a rare hand problem that occurs when the tissue under the skin of the hand toughens and thickens. Over time, knots or cords of thickened tissue form under the skin of the palm extending toward the fingers. These knots or cords bend the finger toward the palm and make it difficult to straighten the affected fingers.
Collagenase is a protein (enzyme) that breaks down the collagen in the knots/cords.
How To Use Collagenase Clostridium Hist. Inj
Read the Medication Guide provided by your healthcare professional before each injection. If you have any questions regarding the information, ask your doctor or pharmacist.
This medication is injected into the tissue knot (cord) of the affected hand by your healthcare provider. Your hand will be wrapped in soft gauze after the injection. Limit hand movement and keep the hand elevated until bedtime. Do not try to straighten, curl, or move the injected finger until your doctor tells you it is okay.
Tell your doctor immediately if you start to feel numbness, tingling, feeling of "pins and needles" in your hand during the procedure.
You must return to your doctor's office within 24 hours after the procedure. Your doctor will check your hand, attempt to straighten the finger if needed, and apply a splint. Wear the splint every night at bedtime as long as directed by your doctor (for up to 4 months). Do finger exercises several times a day exactly as directed. Do not do any strenuous activity with the treated hand until your doctor tells you it is okay.
If you are still unable to straighten your finger after 4 weeks, your doctor may give a repeat injection into the same area of the hand. No more than 3 injections, each 4 weeks apart, should be given in the same area.
Tell your doctor if you have trouble bending the finger after the swelling goes down or problems using your hand.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised May 2010
Copyright(c) 2010 First DataBank, Inc.
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