FROM OUR EXPERTS
Dr. Ravdin et al published a very impressive article in this week's New England Journal of Medicine on hormone replacement therapy (HRT) use and breast cancer rates.
They showed that the incidence (number of new cases) of breast cancer decreased in women who were 50 years of age or older from 2002 through the end of 2004.
They tie this to the decrease in postmenopausal hormone replacement therapy and note that the decrease was largely in the number of new cases of estrogen receptor positive (ER+) tumors.
The data on hormone replacement therapy and its relation to an increased incidence of breast cancer has been well publicized, although my latest take on the most recent iteration was that use for several years after menopause did not really increase the risk of breast cancer – that the increase was in women who had used hormone replacement therapy for 10 years or longer.
The hormone replacement therapy study is an interesting article and well thought out, and the au...
At the San Antonio Breast Cancer Conference in December 2006 a major presentation linked the drop in new cases (incidence) of breast cancer to the decline in the use of postmenopausal hormone replacement therapy . Many were skeptical that this was a true cause and effect, and some postulated that the decline was not due to a decrease in the number of new cancers, but a decrease in their detection due to fewer women having mammograms . If women were less vigilant and not undergoing mammography than the number of new cases would decline - although probably only for a few years. Fewer mammograms would also mean the cancers would be detected at more advanced stages. A new study adds evidence that the decline is due to a decrease in hormone therapy rather than a decrease in mammography - published in the Journal of the National Cancer Institute. Some of the controversy was raised in a series of letters to the New England Journal of Medicine. They pointed o...
A number of new effective hormonal therapies have recently become available. These treatments help stop the hormone estrogen from fueling the growth of breast cancer cells. So which one do you try first? Your best option depends on how you've responded in the past to hormonal therapy, and whether you are still menstruating (having periods regularly).
If the cancer grew or otherwise got worse while you were taking one type of hormonal therapy, your doctor may switch you to a different type of hormonal treatment. But if more than two years has passed since you took the hormonal therapy and had a recurrence, you may still respond to that first medication you were taking. To find out all your choices, read the section below that applies to you.
If you are still having a period each month, you have several choices of hormonal therapy:
treatments that stop your ovaries from making estrogen (ovary shutdown)
tamoxifen AND ovary shutdown
Megace (chemical name:...
You should know
Answers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.