I ran into a problem taking a triptan and antidepressant several days apart. My neurologist had me on a triptan for migraines. It wasn't working for me so he told me to stop using it, wait three days to make sure it was out of my system, then start taking the antidepressant. I did, and the day after taking my first antidepressant dose I woke up with blown pupils (and several other symptoms). We found out from this that I am an extremely slow metabolizer.
So, for those who are slow metabolizer even taking the drugs days apart may cause a problem. I couldn't see for almost two months.
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Teri, thanks for posting this article. I too take anti-depressants and imitrex. I have to say that participating here has been extremely helpful to me. It has taught me how lucky/blessed I am to have the doctors I have! All of this was explained to me by both my psychiatrist and my neurologist (who has also successfully prescribed a tri-cyclic anti-depressant as a migraine prophylactic -- and I MEAN successfully! I barely get a single migraine a month now!). My migraines made me suicidal about 8 years ago; I hope eventually they'll be able to do enough brain research to figure these things out.
Quilter,
You're very welcome! Glad the site is helpful to you.
I've taken triptans with Paxil, and now I take them with Effexor XR. The Effexor XR helps me SO much, both in fighting depression and as a Migraine preventive, so I understand what you're saying very well.
Based on a couple of meetings I've been invited to recently, I think the research situation is going to improve. Heaven knows we need it to.
Thanks for commenting!
Teri