Zomig Nasal Spray Found Effective for Cluster Headaches

Teri Robert @trobert Health Guide
  • A study to be published in the August 28 issue of Neurology, the journal of the American Academy of Neurology, reports Zomig (zolmitriptan) Nasal Spray to be effective for rapid treatment of cluster headaches.


    In a double-blind trial, 151 cluster attacks were treated: 52 attacks with 5 mg ZNS, 49 attacks with 10 mg ZNS, and 50 attacks with placebo. Results were positive with few side effects ocurring during the trial.


      "This is a significant finding and the main endpoint of our study. The 10 milligram dose worked as quickly as 10 minutes in some patients... Cluster headache is an extremely severe headache disorder with enormous unmet treatment needs. Few medications for cluster headache have been systematically tested, and only one, which involves an injection of sumatriptan (Imitrex), has been FDA approved... Because a cluster headache attack builds up to a crescendo within five to 15 minutes, treatment must be rapid and offer significant relief. While the FDA has not approved zolmitriptan nasal spray for use in cluster headaches, it may someday be considered a first-line therapy." (Alan M. Rapoport, MD)


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Published On: August 27, 2007