Monday, May 28, 2012

Migraine Meds Epidrin, Midrin Update 1/28/11

By Teri Robert, Health Guide Friday, January 28, 2011
As promised, I'm still following the situation with the Migraine abortive medications Midrin and Epidrin and other isometheptene mucate / dichloralphenazone / acetaminophen abortive medications. If you haven't been following this situation, or if you want to review the story so far, see Migraine and ...
Changing Dosage or Discontinuing Migraine Meds - Exercise Caution
1/30/11 4:36pm

I just wanted to say thank you, Teri, for your posts which have been such a great help in clearing up all this confusion regarding the "discontinuation" of Midrin and its equivalents. I have taken it for migraines since I was 9 years old, and it is still an important part of my "arsenal", although Relpax is my first-line med now to abort attacks. My fiance takes it too, so we were distressed when neither of us could get our refills this month. I am hoping that the Epidrin company and the FDA will come to some kind of understanding--I for one would be happy to volunteer for a clinical trial if it will get it back on the market sooner! My MD prescibed Fioricet as an alternative, and it does not seem much more effective than Excedrin. Anyway, thanks again for finding out what is really going on!

Teri Robert, Health Guide
1/30/11 11:11pm

laurencat,

 

You're very welcome. I can't do anything about the situation, but I can at least keep relaying the most recent information as I get it.

 

Fioricet really isn't an alternative for Midrin. Midrin can abort a Migraine; Fioricet can't. But then, I think you already know that. The problem is that there's nothing else really like Midrin. That leaves us with the triptans, such as Relpax, or the ergotamines, DHE and Migranal. A bad situation to say the least.

 

Teri

1/30/11 8:55pm

1/31/11

RE: Midrin Capsules and Generic Brand

 

Urgent Request:

 

1.  Are there other generic brands for Midrin besides Excellium?

 

2.  I have been using Midrin successfully for 30 years - nothing else works! 

Now, I'm hearing that it is no longer available.

 

3.  Is any available at all?  Either, A. to my Pharmacy or B. that I could purchase directly from you the Manufacturer?

 

4.  What other Manufacturer's and Store's are there that I can contact?  Names and Email/Phone Numbers?

 

5.  Are you going to be re-distributing it, and if so, when?

 

6.  Why is it not being distributed now?

 

7.  I am in hope that some stores still have some left, or someone!!!

 

8.  Are you re-formulating it for re-release?  And, if so when?

 

9. Is there any way I can get each of the 3 ingredients separately.  Tylenol OTC, I know, but what about the other 2? 

 

 

I am in urgent need of answers.  

Len

 

Moderator's Note: For your security and privacy, please do not post personal information such as email addresses and phone numbers.

Teri Robert, Health Guide
1/30/11 11:13pm

Len,

 

Sorry, but I don't understand this comment. Is this a copy of a letter you sent to someone, or are you asking me these questions?

 

Teri

PS: For your privacy and security, please do not post your email adddress. Please check back here for any replies.

2/ 1/11 6:56pm

2/1/11

 

 

Yes, and Yes.  I have sent it to National Headache Foundation and others with no accurate responses.

 

I would appreciate any responses you might be able to make.

 

It boils down to we need the name and number of the Manufacturer of Prodrin.

 

Other sources don't know and we've tried all the obvious venues.

 

Thanks,

Len

1/31/11 9:20pm

Thanks for the update Teri.  I have been surprised how big of a hole Midrin has left in my arsenal.  I did get a compounded pharmacy prescription filled but it has caffeine in it.  My MD is working with them to come up with something else.  Thanks again for keeping us updates on this, you are the best!

Teri Robert, Health Guide
2/ 1/11 11:20am

Lisa,

 

You're very welcome!

 

Several people have now turned to compounding pharmacies to get medication equivalent to Midrin. They can make it up without caffeine. Midrin and the other equivalent meds contain isometheptene mucate, dichloralphenazone, and acetaminophen.

 

Teri

2/ 1/11 6:58pm

2/1/11

 

Hi There,

 

Where do you get the Ingredients to take to the Compounding companies? 

 

Thanks,

Len

2/ 3/11 12:18pm

Len,

Compounding pharmacies have the ingredients.  My migraine specialist called in a prescription and the pharmacy filled it just like any other pharmacy except they make the medication on site.  Hope that helps.

 

Lisa

2/ 3/11 3:11pm

HI Teri,

The compounding pharmacy I am working with says the Dichloralphenazone is not available to them to use.  I have an appt with my specialist a week from monday, so we will see what else she has up her sleeve.

 

Thanks,

lisa

Teri Robert, Health Guide
2/ 3/11 3:15pm

Thanks for the information, Lisa. I'll be glad to "hear" what your doctor says.

 

I wonder if it's permanently unavailable or if there's another supplier. Some people have been able to get a Midrin equivalent compounded.

 

Teri

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By Teri Robert, Health Guide— Last Modified: 10/29/11, First Published: 01/28/11