I really thanked Teri yesterday for the earlier posting.  My pharmacy had switched my sleep medication on me.  I let them know that I was aware of issues with the Topamax generics so she placed a note in my file for them to try to remain the same.  So, today when I desperately needed to fall asleep in a timely manner needed to adjust my medication and take a little more.  Fortunately, we have planned for that need.  Unfortunately I did not get quite the 7-8 hours I needed, closer to 5-6.  It's really tough working 3rd shift.

It was very comforting to read this in one way.  Now, I don't feel like it is all in my head!  I have taken several meds where they have later changed the mfg, and I tried to tell them they were not the same, but the didn't believe me.  I think this is a very big problem and they are aware of it.  It just isn't talked about.

Hi Teri:

It is interesting to note the statistical "ranges" that generic drugs can vary, legally.  It is astounding.  Now I understand why my endocrinologist insists that I take a BRAND name version of levothyroxine. 

And I have found that with a generic version of Depakote ER, I have needed to add one tablet per week (minimum) to get the same results as I did with the branded version.  Otherwise, I start seeing colored halos around everything, have more visual aura patterns with my migraines, and my left-leg neuropathy returns after a few days. I also "return" to having potent after-images (like I used to have before taking Depakote) if I don't take the extra generic tablet.   I am assuming that if I stay with this particular generic brand, I can expect consistent results from this particular manufacturer.  At least, that is what I hope!  Thanks again.