Topamax and anti depressants

Elizabeth Berger Community Member June 27, 2007
  • I've been reading all the posts about Topamax, and they all seem negative. I get severe nausea and vomiting with my migraines. My doctor prescribed it to me to ward off the vomiting. Has anyone had sucess with topamax with lack of nausea? Everything I've read so far basically said that they get really sick off of it. Also, has anyone had any mood reactions from taking the antidepressants? I have a friend who's on it for depression and she breaks into tears and anger fits out of no where for no reason for the past 2 months. I'm trying to figure out whether i want to do a daily regimen as well. If the side effects from the anti depressants are so bad i might not want to go through with them.

     

     

    Any tips and advice would really help. I just was diagnosed with migraines this year, and I'm trying to figure out how to cope with how dibilitating it can be.

7 Comments
  • Nancy Harris Bonk
    Health Guide
    Jun. 27, 2007

    Hello, and welcome to MyMigraineConnection.com!

     

    Thank you for creating a SharePost. SharePosts are a form of blogging, and there are many things you can do with them. You can share an experience, suggest something that's helped you, use SharePosts as a Migraine and headache journal, and many other things.

     

    Topamax is the most recently approved...

    RHMLucky777

    Read More

    Hello, and welcome to MyMigraineConnection.com!

     

    Thank you for creating a SharePost. SharePosts are a form of blogging, and there are many things you can do with them. You can share an experience, suggest something that's helped you, use SharePosts as a Migraine and headache journal, and many other things.

     

    Topamax is the most recently approved of the four approved for Migraine prevention, and the only one of the four still under patent with generics not yet available in the US. This med works wonders for some people, and in fact has reduced their Migraine attacks they feel their qauality of life goes back up. That is what we all are looking for. When we read, or listen to experiences with medications we can get ourselves into a bit of a problem. It is called the principle of self-fulfilling prophecy. An example of this is when a person is so worried about the potential side effects of a medication that their mind is convinces their body to experience them. I'm not saying you are doing that, but we are having a lot of discussion on our forums, (more on that later in this post)trying to encourage people NOT to read so much into POTENTIAL side effects. If all the side effects happened to everyone all the time for each drug the FDA would never be able to approve any medication! Friends and family mean well, but we need to start out a new medication protocol that works best for us with the best positive attitude we can muster. Does that make any sense?

     

    There are over 100 medications being used for Migraine prevention. So if topamax isn't for you, don't despair, you have more to chose from. Click here: http://www.helpforheadaches.com/articles/prev-meds.htm

     

    Something else to keep in mind that our bodies may need 8-12 weeks to adjust to certain medications before we see a difference in how we are feeling.

     

    We also have a discussion forum that you may want to check out. Especially if you have questions or are looking for information, you may find the interaction on the forum to be quite helpful. To get to the forum, just look for the orange box marked "Manage" and click on the Migraine Forums link. Because our forums are maintained by a third party, you'll need to register for the forum. You can use the same information you used to create your community log-in if you like. If you want to go directly to the forum, you can click HERE.

    Along with your personal "My Home" page and the discussion forum, you'll find links to a great deal of helpful information on the main page of our site, MyMigraineConnection.com.

    If you have any questions, please feel free to post them to the forum or send me a message through my profile.

    Welcome again,

    Nancy Bonk

    MyMigraineConnection.com Expert

     

    PS: If you receive this message from more than one of us, please excuse the overlap. Thanks

  • Anonymous
    james
    Apr. 18, 2009

    I'm very muh against topamax, and I've just started to quit myself. It messes you up, and this doesn't seem to bother the doctors who prescribe it to you. It causes massive weightloss, emotional fluctuations, and worst of all, it makes you about as intellegent as a sack of potatoes.

    I experienced an increase in nausea, but it was not immediate, and it wasn't...

    RHMLucky777

    Read More

    I'm very muh against topamax, and I've just started to quit myself. It messes you up, and this doesn't seem to bother the doctors who prescribe it to you. It causes massive weightloss, emotional fluctuations, and worst of all, it makes you about as intellegent as a sack of potatoes.

    I experienced an increase in nausea, but it was not immediate, and it wasn't severe. However I've read posts by people who didn't say anything about nausea, so it's quite possible that they did not experience any symptoms.

    For me the migraines are so bad I can't sleep at night, and I'd still rather have the headaches then topamax, this time the cure is worse then the disease, that's my advice.

    • Anonymous
      Anonymous
      Dec. 04, 2009

      So I just started the topmax 3 days ago.  No side effects and but I'm afraid it is also not helping with the headache.  Although the headache I am feeling coming on now may be pms related.  Should the drug help this as well?  Is the drug suppose to be immediately effective.  I started on the lowest does and may need to increase although...

      RHMLucky777

      Read More

      So I just started the topmax 3 days ago.  No side effects and but I'm afraid it is also not helping with the headache.  Although the headache I am feeling coming on now may be pms related.  Should the drug help this as well?  Is the drug suppose to be immediately effective.  I started on the lowest does and may need to increase although I was hoping not to.  I think I didn't ask the Dr. enough questions.

  • Anonymous
    Andrea W.
    Apr. 07, 2008
    Im currently on topamax for my migraines and it gives me killer nausea and dizzines to the point where i cant function. Ive only been on it for going on 3 weeks now im wondering if your body ever gets use to it or if it goes away? I cant eat either. Ive lost about 10lbs.
  • Marlene Sylvester
    Jul. 05, 2007

    Elizabeth,



    I started topa a little over 5 years ago. Like most of the posters it was a very difficult and challenging journey for me too. But, when I started topa I also started with migraines that were so out of control that I went into a very convulsive state of uncontrolling vomiting, sweat just rolling out of me, my words were no longer available, and the...

    RHMLucky777

    Read More

    Elizabeth,



    I started topa a little over 5 years ago. Like most of the posters it was a very difficult and challenging journey for me too. But, when I started topa I also started with migraines that were so out of control that I went into a very convulsive state of uncontrolling vomiting, sweat just rolling out of me, my words were no longer available, and the pain, well who can describe that.


    For some topa gave only a little nausea and some tingling. For others they lost weight. For me I had every s/e that topa had to offer except the weight loss. Yes topa can and does intensify many of your feelings and everything going on in your daily life. According to the makers of the med this is only tempory. The cognitive seems to linger on and off with the increases.


    Now, if you work with your doc you can help keep some of those s/e from happening so intensly by not increasing your doses too quickly. If you notice that you are acting or behaving differently ask your doc to cut back on your dose until you are feeling more in control.


    Topa does come in 15mg capsules. That is a real good way to start and do your increases instead of the 25mg tablet. When you do go to the tablet or do go to the 100mg table or 200mg table and notice any kind of affects remember that by going to the tablet there is the coating and filling change.


    Topa is a very odd drug. It does take some serious thinking as any drug does. It does not interact with other drugs is one main reason it is a good drug to prescribe. Now sometimes other drugs are prescribed along with topa to help with the s/e. That you will need to discuss with your doctor.


    So, for me topa has helped in the intensity of my migraine. It also has helped in keeping the volume of migraines that I get down. I know longer get them in the way that I use to get them. I still get them though and when I do I use the Imitrex injection and usually the migraine is gone in about 15 minutes.


    I hope my thoughts on this have been helpful. Oh, most people posting are looking for help that is probably why you don't see so much in positive posting of topa.



    Marlene227


    (saw there is another Marlene)

  • Anonymous
    doah
    Jun. 28, 2007

    As Nancy said everyone is going to react different to medication. I worked up to 200 mg of Topamax and say almost no side effects. I had the tingling in my feet. While annoying, it went away after a few minutes. There were a few times it took me a few seconds to come up with the correct word in a sentence but I can't say that was really from the med. It...

    RHMLucky777

    Read More

    As Nancy said everyone is going to react different to medication. I worked up to 200 mg of Topamax and say almost no side effects. I had the tingling in my feet. While annoying, it went away after a few minutes. There were a few times it took me a few seconds to come up with the correct word in a sentence but I can't say that was really from the med. It also did not help my headaches.


    Remember you wont know if it works for you unless you try it. I'd be comforted to know that not everyone has bad effects from any med.


    Good luck.

  • Chronic HA
    Jun. 28, 2007

    Your concerns are very justified. Topamax caused me serious cognitive issues. First was the tingling and noticeable memory loss. I was told the memory loss could be from and number of things including aging or my HA. I was not concerned about the tingling as long as I knew the cause and that it was not a serious medical problem. The Topamax did help some, but...

    RHMLucky777

    Read More

    Your concerns are very justified. Topamax caused me serious cognitive issues. First was the tingling and noticeable memory loss. I was told the memory loss could be from and number of things including aging or my HA. I was not concerned about the tingling as long as I knew the cause and that it was not a serious medical problem. The Topamax did help some, but I still experienced severe HAs daily. They finally got very low using Topamax in addition to Seroquel and Verapamil.


    I was not aware what Topamax was doing to me before the others were added, even though my family was wondering about my behavior. I was eventually diagnosed as bipolar and manic. (No family history of either) The Drs denied it was the Topamax. My wife and son researched my meds and diagnosed the problem as Topamax poisoning. They convinced me to work my way off the Topamax and noticed improvement right away.


    It took me 2 months after I was off to realize how bad I had been. I became very depressed and the meds did not help for that. I had not worked for 5 months at that point. I was on it for 8 months total. I lost my job 6 months after starting it. 4 months after I had quit, I was able to start working part time again. They don’t know what the half life of this stuff is. I was told it would be out of my system in 2 weeks. I believe the extended depression was a Topamax side effect. I have always been one of the lucky few who wake up every morning in a good mood, every day, all year long, year after year. I had never experienced anything remotely close to depression until post-Topamax.


    Now a little over two years later, I am pretty much my self again. I still mix up some words and spelling to a minor degree. Some times I notice it and sometimes I cannot believe what I have written, because there are so many basis errors. I was on 400 mg / day. The Dr took me up there in a matter of about a month or so.


    If it were not for my wife and son, I probably would not be alive today. I experienced a feeling impending doom 3 times near the end of Topamax. I knew I was in the dying process, I needed help and I didn’t know what to do.


    It is probably worth a try. Many people must be helped if you read all the testimonials. Now, my wife watches me very closely for any kind of change. She is quite concerned when I participate in migraine studies, but I haven’t tried any new drugs in them. I would certainly have someone very close to you watch for any sign of change in your personality. Any feeling of anxiety, paranoia, tingling in extremities, weight loss, changes in your spending habits, anything not normal for you. IT IS THE TOPAMAX in spite of what the drs may say. I don’t take any of the bipolar drugs prescribed because I’m not bipolar, I was poisoned by Topamax. My wife saved an acquaintance’s husband who started off acting similar to the way I did. His dr said it was not the Topamax too, but he went right back to normal.


    You are responsible for your own health. You can always work your way back off. I just wish I had known then, what I know now. I was too far gone to help myself when I quit Topamax. Be sure to have some one observe you for changes in your personality. Use you own best judgment while you still have it.


    Take care, good luck. Bob

How to Take Charge Living Well with Migraines

Most Popular

http://www.healthcentral.com/migraine/cf/slideshows/10-ways-for-migraineurs-to-sneak-in-some-exercise
Migraine Medications and Treatments
Exercise Tips for Migraineurs