I had rebound headaches for years and my "specialist" claimed they were not rebound.  For me, they came on early am, 4 or 5 am and grew intense very quickly until I took more Imitrex/Amerge/Frova.  This happened almost every day.

My cousin (an RN in Fresno) told me a little bit about DHE 45 and the IV treatment. She thought it was for headaches, not rebounds. 

I did some reseach on DHE 45 on the internet and printed out the pertintent pages.  I visited a new physician in my specialist's practice and showed him the literature.  He had heard of the DHE 45.  I begged him to write me a script and that I could give myself shots at home and skip the hospital treament.  He did. My husband gave me the first injection in my thigh.  It burned so bad I hyperventilated and passed out. 

The next day I gave myself the injection and took half a dose.  I stuck with half a does for several days, then went to 1/3 of a dose, then 1/4, then 1/5 of a dose.  I gave myself 1/5 of a dose injection for over a year and did not have one headache in that time period.  It was a glorious year! 

I thought the headaches were gone so I stopped the DHE and the headaches came right back.  Now I have been unable to achieve the same results with DHE 45.  I am looking for alternatives.  I am so sorry I ever stopped taking the DHE in the first place. 

But it will stop the rebounds and you can do it yourself.  Also, it hurts a lot less if you take the shot in the stomach in stead of the thigh. 

I hope this helps.