Seroquel for migraines?

angel30 Community Member July 24, 2007
  • My doctor gave me Seroquel today for migraines.  I don't think I've ever heard of this being prescribed for headaches. Has anyone else tried this? What were the results?
19 Comments
  • Anonymous
    ArtistLike
    Feb. 23, 2012

    Last November out of nowhere, I started getting what most closely matches the description of cluster headaches--they would almost always come around 7/7:30 p.m. and build slowly to an excruciating pain that would last about 90 minutes and then gradually subside.  One week it would happen twice, the next week it happened five nights out of seven.  I've...

    RHMLucky777

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    Last November out of nowhere, I started getting what most closely matches the description of cluster headaches--they would almost always come around 7/7:30 p.m. and build slowly to an excruciating pain that would last about 90 minutes and then gradually subside.  One week it would happen twice, the next week it happened five nights out of seven.  I've also been experiencing significant neurological problems for about two years, and other than an optic nerve problem and abnormally brisk knee reflexes and spinal arthritis (I'm 33!!), no neuro tests revealed anything out of the ordinary.  I've been seeing a psychiatrist for about a year for extreme depression and anxiety and when I told her about my cluster headaches at the end of November, she asked if I would try taking Seroquel--just 25mg.  I'd try ANYTHING, I told her.  She had long suspected conversion disorder as the cause of my neurological problems, but because they're so real, I couldn't believe that.   Two days after I took my first Seroquel pill, I got my last cluster headache in my right eye.  It hasn't happened since, and it's been three months now.  I don't know for sure that the Seroquel is what stopped them (and I still get the other neurological problems on and off, by the way), but it's quite a coincidence if it's not the medication.  Even if it's a placebo effect, that's fine with me; the only thing I can compare the cluster headache pain to would be the worst toothache I've ever had--like a live wire in my eyeball.

  • acheybreaky
    Apr. 07, 2010

    My neurologist that specializes in migraines recently put me on Seroquel and the results have been dramatic.  Yes, I sleep like the dead and it's difficult to wake up. I'm adjusting the time I take the med at night so I can get up and function as I need to.  But it's working.  I suffer from DAILY migraines after an accident converted my prior...

    RHMLucky777

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    My neurologist that specializes in migraines recently put me on Seroquel and the results have been dramatic.  Yes, I sleep like the dead and it's difficult to wake up. I'm adjusting the time I take the med at night so I can get up and function as I need to.  But it's working.  I suffer from DAILY migraines after an accident converted my prior occasional migraines (1-3x/month) to non-stop daily occurrence due to a head injury.  This has been going on for a year and I've tried all kinds of drugs, therapies and treatments.  Things that would start to give me relief would have unbearable stomach symptoms and just lessen the pain, not fully get rid of the headache.

     

    I've only been on Seroquel a few weeks and I've already had several pain-free days in a row.  The headaches do come back but I can function and I know that relief is in sight.  I'm hopeful that this RX will continue to work and get better!

    • Manic Monday
      Jan. 10, 2011

      I was originally prescribed Seroquel for my Bipolar I disorder (500mg/day) and for the first time in my life noticed that I did not have a headache. I am 34 and have lived with a headache of one degree or another my entire life.  I can not begin to tell you how amazing the feeling was.  Unfortunately, I no longer take Seroquel because it did not adequately...

      RHMLucky777

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      I was originally prescribed Seroquel for my Bipolar I disorder (500mg/day) and for the first time in my life noticed that I did not have a headache. I am 34 and have lived with a headache of one degree or another my entire life.  I can not begin to tell you how amazing the feeling was.  Unfortunately, I no longer take Seroquel because it did not adequately control my moods and caused me to gain 14 pounds (which was not acceptable to me), so the headaches are back.  I have another bipolar friend and she told me that Seroquel worked well for her migraines as well.  As I have tried the IR version and the XR version, I did note that the XR does not help for migraines even though the immediate release, the sedating one, does.

  • Anonymous
    amoredemialma
    Jan. 20, 2010

    I too just started seroquel for my migrain treatement.  This is my 3rd or 4th round of medications to try, so I am not sure if it is working yet.  One thing I did notice, is in the middle of a migraine that wont break, it suddenly got worse about 35 min later.  Has anyone noticed this phenomenon of an instant headache after taking a dose of seroquel? ...

    RHMLucky777

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    I too just started seroquel for my migrain treatement.  This is my 3rd or 4th round of medications to try, so I am not sure if it is working yet.  One thing I did notice, is in the middle of a migraine that wont break, it suddenly got worse about 35 min later.  Has anyone noticed this phenomenon of an instant headache after taking a dose of seroquel?  Hope it works for you!

  • Cammy
    Nov. 13, 2009

    My husband takes Seroquel.  He sleeps really hard... seems to help his migraines, but has put on 30 pounds with this medication.  He's now obese.... what to do?

    • equineilusa
      Feb. 19, 2012

      I am curious what course of action you decided to take due to the undesired weight gain. My migraines have been very well controlled on e lowest dose of Seroquel...but the weight gain and excessive a.m. druggyzombie effect prompts me to stop this drug soon. have tried everything as prophylactic for migraines. seroquel has helped the most...unfortunately. any...

      RHMLucky777

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      I am curious what course of action you decided to take due to the undesired weight gain. My migraines have been very well controlled on e lowest dose of Seroquel...but the weight gain and excessive a.m. druggy\zombie effect prompts me to stop this drug soon. have tried everything as prophylactic for migraines. seroquel has helped the most...unfortunately. any suggestions??? 

  • Anonymous
    laurel
    Feb. 13, 2008
    I don't know if you've already received a response, considering how long ago your posting was, but I wanted to give my opinion anyway. I've been on Seroquel in the past and it actually gave me headaches. It's an antipsychotic medication; I've never heard about it's use in migraine treatment. Was it your physician's first choice?
  • Anonymous
    Rebecca Funk
    Jan. 29, 2008

    I was just prescribed this drug starting tonight. I see my neurologist in 3 days again. I called him complaining of daily headaches early in the morning on awaking. I have already tried many triptans and daily medications for migraines. I have even taken all the vitamins suggested to help migraines. Some of these posts scare me about taking Seroquel before...

    RHMLucky777

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    I was just prescribed this drug starting tonight. I see my neurologist in 3 days again. I called him complaining of daily headaches early in the morning on awaking. I have already tried many triptans and daily medications for migraines. I have even taken all the vitamins suggested to help migraines. Some of these posts scare me about taking Seroquel before bed. My headaches are so painful I want to try anything. I have recently been taking Frova and darvocet when needed. Any help would be appreciated.

    Thanks 

    • Anonymous
      CC- Pittsburgh
      Feb. 07, 2008

      My neurologist only prescribed my Seroquel only as a "rescue drug" to induce sleep when my acute drugs are not working.  Not on a daily basis.  As daily prevention I take Topomax, Effexor and Magnesium. For acute attacks, triptans do not work for me, I take IM DHE.  Sometime's  I have to use Decadron for a few days. I used...

      RHMLucky777

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      My neurologist only prescribed my Seroquel only as a "rescue drug" to induce sleep when my acute drugs are not working.  Not on a daily basis.  As daily prevention I take Topomax, Effexor and Magnesium. For acute attacks, triptans do not work for me, I take IM DHE.  Sometime's  I have to use Decadron for a few days. I used to have "good old classic migraines" that reacted just fine to Triptans, but now in my 30's they are Hormonal, and very persnickity.  I can go 3 months without one then 2-3 weeks with one everyday or every 1-2 days.  Absolutely frustrating!!!

      I would discuss with your neurologist not taking Darvocet, you maybe getting rebound headaches.  Any NSAID use could cause this. That is what my neurologist believes, and it works for me.  Just a FYI.

  • Anonymous
    dani
    Jan. 27, 2008
    I would never see that doc again. Seroquel GAVE me a BAD headache, up the neck, so stiff neck, I was nauseated, barfed. Threw them in the garbage. Plus Seroquel CAUSES you to become diabetic. It should be recalled, discontinued, banned. In fact there is a class action lawsuit against the drug company for not disclosing it....
    RHMLucky777
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    I would never see that doc again. Seroquel GAVE me a BAD headache, up the neck, so stiff neck, I was nauseated, barfed. Threw them in the garbage. Plus Seroquel CAUSES you to become diabetic. It should be recalled, discontinued, banned. In fact there is a class action lawsuit against the drug company for not disclosing it. Plus MY dose was tiny, tiny. Like a 25mg pill my doc told me to cut in half or quarters. (I have a pretty good pill splitter), (I am an ICU registered Nurse.) The dose goes as high as like 200-400 mg for like really mentally ill people, like split personalities, paranoids, people who hear voices. It was prescibed to me when I first started on Paxil, years ago, right after 9-11-2001, the most stressfull day for so many of us. The doc (this was way B4 the info about diabetes came out), she had prescribed it to me, thinking it would help me sleep better until the Paxil kicked in, as it sometimes takes a few weeks. (for the Paxil). She didnt wanna give me something good like xanax or something. Sometimes Docs think they know whats best when they really dont. Get 2nd opinions, listen 2 your gut, if there is a language barrier (like Indian, etc), there is likely to be a cultural barrier. There is absolutely NO indication for headaches, migraine or otherwise in the Seroquel literature. It is for mentally ill people that hear voice &/or are psycotic. Fire that doc & report him/her to medical board in your state. You have rights as a consumer & a patient. Best Wishes, Take Care
    • Anonymous
      CC
      Feb. 07, 2008

      I too am an ICU RN, and have been fighting with hormonal migraines for about 5 yrs now.  I used to just get classic migraines since my teens that Triptans helped, but no more.  Now , I am on several preventative meds daily including Topomax.  And for my acute attacks, IM DHE that I give my self and for a "rescue drug" Seroquel. ...

      RHMLucky777

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      I too am an ICU RN, and have been fighting with hormonal migraines for about 5 yrs now.  I used to just get classic migraines since my teens that Triptans helped, but no more.  Now , I am on several preventative meds daily including Topomax.  And for my acute attacks, IM DHE that I give my self and for a "rescue drug" Seroquel.  This is used to induce sleep as one of my last resorts, and it works.  The lawsuit that you spoke of was retracted, there is NO evidence that it causes DM.  The NIH- Neurology and Magnum have several articles on the use of Seroquel for Migraines.  Please refer.

      Not everyone, neurologist, has a cookie cutter treatment for Migraines.  What works for one person may not work for another.   Just an FYI.

  • Anonymous
    Nicole
    Nov. 21, 2007
    I was prescribed Seroquel for insomnia, but I was told by my doctor that with the Zonegran(seizure Medication) I was taking that these two meds worked well together and they have completely changed my life-I have only had 1 migraine that I had to go to the ER for in 4 months and this had become a typical occurence every month to month and half.  I feel...
    RHMLucky777
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    I was prescribed Seroquel for insomnia, but I was told by my doctor that with the Zonegran(seizure Medication) I was taking that these two meds worked well together and they have completely changed my life-I have only had 1 migraine that I had to go to the ER for in 4 months and this had become a typical occurence every month to month and half.  I feel like a new person!!!
  • Anonymous
    Beth
    Nov. 18, 2007
    my doctor gave me seroquel to use for my migraines and it helps me "sleep them off" although my husband hates it when i take it because he has a hard time waking me up.  but the whole point in taking it is to sleep and not have to go to the ER so i would suggest trying it
  • Anonymous
    Anonymous
    Aug. 22, 2007

    I don't know about migraines, but it has helped me chronic cluster headaches.  After suffering for over 30 years with cluster headaches, going through 8 different 'preventative' medications with no help, and no relief from the 'abortives', I finally have found something that works.  It is an absolute "God-send". ...

    RHMLucky777

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    I don't know about migraines, but it has helped me chronic cluster headaches.  After suffering for over 30 years with cluster headaches, going through 8 different 'preventative' medications with no help, and no relief from the 'abortives', I finally have found something that works.  It is an absolute "God-send". 

     

    I would recommend giving it a try.

    • phred
      Oct. 05, 2007

      That is a very interesting and helpful

      comment regarding seroquel - that it

      greatly helped your cluster headache.

       

      In my experience, the cluster headache

      is quite different from the migraine

      headache - when it comes to treatment.

       

      May explain why the other person had

      such horrible side effects. That person

      has migraine headaches.

       

      (Just as an aside here,...

      RHMLucky777

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      That is a very interesting and helpful

      comment regarding seroquel - that it

      greatly helped your cluster headache.

       

      In my experience, the cluster headache

      is quite different from the migraine

      headache - when it comes to treatment.

       

      May explain why the other person had

      such horrible side effects. That person

      has migraine headaches.

       

      (Just as an aside here, that is one thing

      that is great about Midrin; either it

      works or it doesn't do a thing.  There

      are none of these vicious side effects.)

       

      Thanks for your contribution.

       

       

  • Anonymous
    Anonymous
    Aug. 21, 2007
    My neurologist prescribed me it for my intense migraines. I took it the other night b/c I was having an awful migraine. BAD SIDE EFFECTs for me. Anxiety, very jittery, couldn't keep my legs still, but feeled really "drugged" I almost went to the ER when I started having pains in my left arm and my left fingers starting tingling. No relief from...
    RHMLucky777
    Read More
    My neurologist prescribed me it for my intense migraines. I took it the other night b/c I was having an awful migraine. BAD SIDE EFFECTs for me. Anxiety, very jittery, couldn't keep my legs still, but feeled really "drugged" I almost went to the ER when I started having pains in my left arm and my left fingers starting tingling. No relief from the migraine however. Any ideas why I reacted this way... does this normally happen. As of now I will never take seroquil for migraine relief. email me with suggestions or comments. drewfy13@yahoo.com
  • jessiel1979
    Jul. 31, 2007
    My doctor wanted to give me that and I decided not to take it because I heard from a lot of people including my sisters,  boyfriend, that you gain weight and feel like a zombie.  He also said that he can't wake up after taking it the night before even the smallest dose.  He actually lost a job from being late all the time because...
    RHMLucky777
    Read More
    My doctor wanted to give me that and I decided not to take it because I heard from a lot of people including my sisters,  boyfriend, that you gain weight and feel like a zombie.  He also said that he can't wake up after taking it the night before even the smallest dose.  He actually lost a job from being late all the time because of over sleeping.  If you took it let me know how it's going.  I am interested in how it makes you feel.  Comment me back at my sharepost.  I hope everything is going well for you and I hope it helps you.
  • naykay
    Jul. 25, 2007

    Hello!  I have never heard of Seroquel being prescribed for migraines.  I know it has recently been prescribed for bi-polar or manic-depressive disorder and maybe one of its side effects is reducing pain.  I know Cymbalta helps me with pain management in my neck and back.  If I find any info about this, I will send you another post. ...

    RHMLucky777

    Read More

    Hello!  I have never heard of Seroquel being prescribed for migraines.  I know it has recently been prescribed for bi-polar or manic-depressive disorder and maybe one of its side effects is reducing pain.  I know Cymbalta helps me with pain management in my neck and back.  If I find any info about this, I will send you another post.  Good luck in yor search for more info!

     

    Kay 

  • Nancy Harris Bonk
    Jul. 24, 2007

    Hi Angel30,

     

    We have other members here who have been prescribed Seroquel for Migraine and have had some success with it. The best thing to do would be to post this question to the forum. That way you will be able to have a "conversation" about how this medication works for them.

     

     

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