Oh My, just came off a 3 week Migraine that took everything out of me! NONE of my meds were working......I ended up in the ER.......I don't even remember the ride home. I tapered off everything I was taking, the Topamax just stopped working and my pain was even worse on it the last few weeks! I was taking imetrex every day with only an hour or 2 of minimal relief...then the pain came back even stronger. Thought I found my miracle with the Topamax........but no! It took a few days and then I felt myself coming back to life. The pounding burning pain gone all the blinding aura gone. My blood pressure is back to normal now. I am back to the basics Prozac and imitrex injections. The heat is on in the desert and this is the test, I am good so far. Only 1 attack and the imitrex knocked it out, the shots are back to what saves me. I would rather stick my arm and deal with anything that comes with the imitrex, than have a migraine. The Topamax is a life saver for many, I really wish I could have stuck with it. Prozac to the rescue and extreme migraine diet and I guess I am living with it. 
Are you taking Imitrex every day? Any preventive medication you take will not work if you have Medication Overuse Headace, I'm sorry to say. It is like a double edge sword, we want the pain to stop, but if we take certain OTC and prescriptions more than 2-3 days a week we run the risk of MOH.
We have information on that HERE.
I hope you feel better.
Hi,
I was on Topamax for the prevention, I was in 3 weeks of killing pain after several days and a visit to urgent care, I had to takethe imitrex every 24 hours to keep me alive. Its the only time I have taken so much.
The ER is what I had to do to break the pain and then heavy pain meds.
Then I put a stop to the Topamax and after a few days the migraine did not return.
The prozac and diet is now what I have to do. If I have trouble will get back on a beta blocker. I have had the migraine attacks for over 30 years since very young.
I had every kind of test and tons of doctors. Every few years I need to switch out what has been working when the migraine cycle gets out of control.
Somehow the Topamax was creating such a killer pain nothing was working.
It also caused extreme anxiety and a raise in blood pressure. I gave it my best shot but am done with Topamax.
I have used imitrex for the onset for almost 15 years and now it is working again just fine.......amazing. I use it as little as possible under my doctors advice and am fully aware of the horrible downward spiral of over use of medication. I feel so much better now on the prozac without the anxiety of an attack. Now I can work on prevention again, the whole mind body connection.
Thank you so much.
Back from the brink.
Cathy