My neuro put me on Amerge for hormonal migraines. My doc did not put me on an abortive since I had chest pains and breathing issues with Imitrex. I have been on Amerge years ago and never had any issues with it at that time. And really I need something to deal with the hormonal migraines, as Lyrica does not do anything to them and I am returning to work as soon as my boss gets back to me. In order to return to work I must have a way to effectively manage any migraine that comes in order to not miss work.
Anyway, I tried out the Amerge to see how effective it would be and to see any effects it may have, so I know how to handle it when I return to work. And it is not so great. It does cause chest pains, about fifteen minutes after taking it. It does cause breathing problems... not like Asthma with issues on the exhale and wheezing... but just not getting enough air. My heart goes a little weird and then later on it leaves me with palapatations. It also makes me extremely tired after it gets rid of the migraine, so tired I am dopy like I have slept for hours and start falling alseep. I am hoping the sleepy effect will not last. As for the others, well as long as I stay upright, they go away.
I have read the info on abortives and I know chest pains are one of the side effects that usually means you cannot take it any more. Yet I need to manage the migraines I have no choice in the matter. Having experienced some nasty angina pain in the past I don't tend to get riled up over it and certainly would not run to the ER over it either. I honestly do not think it would be dangerous to continue with the Amerge even with this effect, as long as I do not take it twice in a day. And being used to enduring any number of side effects over the years, I get used to letting a lot of these things slide, unless something jars me like Imitrex was getting. So it may be stupid to keep taking an abortive that causes chest pains, I am just not sure this side effect is really doing anything harmful to my heart, and since I have to return to work I am willing to risk it.


The first 2-3 times I took Imitrex I experienced a tightness in my chest. I cannot say it was pain. I no longer have that but continue to have heaviness in my left arm when I take it.
I have tried Amerge and it did nothing for the migraines I took it for.
Some additional food for thought for you. I take Frova for menstral migraines, but I take it daily during the course of my period. My neurologist, who is a migraine specialist, perscribed the use of the Frova this way. He was specific in the use of the Frova due to the lenght of time it stays in the system. It has worked well. I do feel there may be issues with medication overuse headaches, but it's difficult to fully tell that.
Take care and good luck. It is difficult to find the right medications.
Cindy