How are serotonin levels measured?

Ask the Clinician Health Pro
  • Full Question:

    i was reading an article of yours "Migraine Term of the Day: Serotonin".


    I would like to know how Serotonin levels are measured? in my country, Pakistan. there is no such test exists. They have 5-HIAA (Urine test) and Platelets (Blood Test) are available. Both test doesn't show Serotonin Levels.


    Please let me know how to measure Serotonin Level. Regards, Bassam.


    Full Answer:

    Dear Bassam;


    I spent 4-5 years of my life studying serotonin, and the only way to reliably measure it is to freeze it at -100C with special precautions to prevent destruction of 5HT. As a practical matter, it wouldn't help in therapy or choice of approaches to treat headaches and Migraines.

    Add This Infographic to Your Website or Blog With This Code:


    Good luck,
    John Claude Krusz



    To review other questions from our Ask the Clinician Column,
     browse the Ask the Clinician archives.


    If you need help finding a  Migraine and headache specialist,
     visit our listing of Patient Recommended Specialists.



    About Ask the Clinician:

    Dr. Krusz is a recognized expert in the fields of headache and  Migraine treatment and pain treatment. Each week, he and Lead Expert Teri Robert, team up to answer your questions about headaches and  Migraines. You can read more about Dr. Krusz or more about Teri Robert.


    If you have a question, please click HERE. Accepted questions will be answered by publishing the answers here. Due to the number of questions submitted, no questions will be answered privately, and questions will be accepted only when submitted via THIS FORM. Please do not submit questions via email, private message, or SharePost comments. Thank you.


    Please note: We cannot handle emergencies or diagnose via the Internet. Please do not ask us to diagnose; see your physician for diagnosis.


    We hope you find this general medical and health information useful, but this Q & A is meant to support not replace the professional medical advice you receive from your doctor. For all personal medical and health matters, including decisions about diagnoses, medications and other treatment options, you should always consult your doctor. See full Disclaimer.


    Follow Teri on    or 


    Page copy protected against web site content infringement by Copyscape© Teri Robert and J.C. Krusz, 2011.
    Last updated June 13, 2011.

Published On: June 13, 2011