Doctor changed my acute Migraine medication from Maxalt to Zomig?

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  • Full Question:

    I have been taking maxalt lyophilisate 10mg for the last 11 years for acute migraine since I was 46 years old. Just recently my doctor has changed my repeat prescription to Zolmitriptan 2.5mg. Is this because i have been taking the same drug for so long or is it a better tablet to take although the dosage is smaller. I am wary of taking the drug in case it is not as good as Maxalt. I have read up on both of the tablets and i am still not sure? perhaps you could enlighten me. Glenda.


    Full Answer:

    Dear Glenda;


    Comparing 10 mg of one medication to 2.5 mg of another isn't an accurate comparison. The effective dosages don't necessarily correlate to the same number of mg from one medication to the next.

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    Only your doctor can tell you why he changed your prescription from Maxalt to Zomig. You didn't say if Maxalt has become less effective for you over the years. If so, that could be the reason for the change.


    Maxalt and Zomig are both triptan medications. The primary difference between them is that they bind to different combinations of serotonin receptors. Neither is "better" than the other. Some people will find that one works better for them than the other because of the way each person's body responds to them. The only way to find out if Zomig works as well for you as Maxalt has worked is to try it.


    Good luck,
    John Claude Krusz and Teri Robert



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    About Ask the Clinician:

    Dr. Krusz is a recognized expert in the fields of headache and  Migraine treatment and pain treatment. Each week, he and Lead Expert Teri Robert, team up to answer your questions about headaches and  Migraines. You can read more about Dr. Krusz or more about Teri Robert.


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    Last updated September 17, 2013.

Published On: September 17, 2013