Full Question:

I have had migraines since age 19 and have tried every preventivemedication to stop them but nothing has worked. Over two years ago I found out that I had major depression and in that period I started have migraines when I woke up. The depression has caused me to have major sleep problems to where I go to sleep after midnight and wake up around four a.m. I was having problems with different sleep medications with side effects and bad dreams, so I was put on Seroquel 100mg. to see if it would work. The problem with it was that after I went to sleep it worked too good, I could not function until the afternoon of the next day, but during that period of time I was using it most of the waking up migraines disappeared. I am wondering if the medication caused the migraines to stop, or was it because of the amount to sound sleep that I was getting? Chris.

Answer:

Dear Chris;
Probably some of each. My good friend and colleague, Dr. Jan Brandes from Nashville published that Seroquel could help reduce migraines. That was at 50mg at night. And it helped sleep. Your dose should or might have been reduced and the good effects might still have been there, with less daytime drowsiness. Getting to the most effective dose with the fewest side effects is part of the challenge.
Good luck,
John Claude Krusz and Teri Robert

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