Top 75 Migraine and Headache Questions, #56

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  • Full Question:
    What normally goes on in the brain prior to, during, and after a migraine? Cathy.


    Dear Cathy;

    Entire books could be and have been written on this subject. It's quite impossible to answer it in this venue. Here's an overview: Migraineurs have overactive neurons in their brains. When they encounter a trigger, those neurons fire in a wave across the brain, starting a chain reaction. The chain reaction includes dilation of blood vessels in the brain; inflammation of nerves and tissue surrounding the brain; and disturbances in the balance of neurotransmitters including serotonin, norepinephrine, and dopamine. All the events in this chain reaction cause the various symptoms of a Migraine attack.
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    Good luck,
    John Claude Krusz and Teri Robert

    About Ask the Clinician:

    Dr. Krusz is a recognized expert in the fields of headache and migraine treatment and pain treatment. Each week, he and Lead Expert Teri Robert, team up to answer your questions about headaches and Migraines. You can read more about Dr. Krusz or more about Teri Robert. If you have a question for this section of our site, please click HERE. Accepted questions will be answered by publishing the answers here. No questions will be answered privately.

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Published On: April 08, 2007