Fewer cognitive side effects with Zonegran than Topamax?

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    I have been taking 100 mg Topamax for migraine prevention-however I am experiencing cognitive side effects- memory- recall, some concentration - short term memory- etc. I have done some research and inquired about Zonegran as an alternative- is it the case that the cognitive side effects are less with Zonegran? Thanks, Dee.





    Dear Dee;


    In clinical trials, the incidence of cognitive side effects was significantly lower with Zonegran than Topamax. In our practice, we see very good results with Zonegran with far fewer side effects.


    Obviously, not everyone will have the same experience, but both the clinical trials and our practice experience would confirm fewer cognitive side effects with Zonegran. By they way, it is also available as generic zonisamide.

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    John Claude Krusz and Teri Robert


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    Last updated September 2, 2009.

Published On: September 02, 2009