Full Question:
I have been taking Imitrex 2 - 4 per month for about 10 years. I have had joint stiffness commonly after taking it. However, I am a professional martial artist as well as a Nurse Practitioner and after taking Imitrex, my flexibility has decreased by about 50% for a week or so, ...


I read Peggy's post and identified with the joint, but wanted her to know that I get stiff joints no matter which tripan I take. I attribute it to the migraine, not the medications.
It happened when I was in "trials" with treatments and preventative medications other than triptans. I think the stiffness is in my joints/ligaments is related to the migraine and to a prolonged postdrome after the migraine. When this happens (and it happens monthly because I have hormonal migraines), I feel like I have the flu, or have been hit by a truck. Muscle aches and extreme stiffness of joints/ligaments occur during and after my migraine cycle, regardless of which medication I take.