Joint stiffness for a week after Imitrex?

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    I have been taking Imitrex 2 - 4 per month for about 10 years. I have had joint stiffness commonly after taking it. However, I am a professional martial artist as well as a Nurse Practitioner and after taking Imitrex, my flexibility has decreased by about 50% for a week or so, then I can finally get stretched out again, I take another Imitrex, and then I cannot stretch. Is there any post-marketing information about this? Peggy.


    Dear Peggy;

    I know of no such information on Imitrex. After all, it is gone from the body in 8 - 10 hours.

    Perhaps another triptan might avoid your (rather long) symptoms after Imitrex. There are six other medications in the triptan family-- Maxalt, Zomig, Amerge, Relpax, Axert, and Frova. Each of the triptans binds to different combinations of serotonin receptors, which is why our bodies may respond differently to each of them. It could be worth discussing the ones you haven't tried with your doctor.

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    John Claude Krusz and Teri Robert


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    Last updated November 14, 2009.

Published On: November 14, 2009