Health care professionals depend on good sources of information to keep up-to-date on evidence-based medicine. One of the most reliable publications comes from the Cochrane Collaboration . Everyone pays attention when they publish a study. The Cochrane Collaboration is a group of over 11,500 volunteers who systematically review all relevant randomized controlled trials on a specific topic. The people in the group are located in more than 90 countries. They also study the results of non-randomized, observational studies. The results of these systematic reviews are published in the Cochrane Library. In this study, the use of nonsteroidal antiinflammatory drugs (NSAIDs) for low back pain (LBP) was reviewed. The goals were to 1) look for effects of NSAIDs and 2) find out which type of NSAID works the best. Specifically, COX-2 inhibiting NSAIDs were considered. These drugs have a lower risk of gastrointestinal side effects. For this reason, they have recently become more popular than the trad...
in The Daily Mail highlighted a study conducted by the
University of Tampere in Finland that suggests that men who take
daily doses of pain medications, including ibuprofen, are at a
higher risk of erectile dysfunction.
Urologist Dr. David Knowles comments on the study and tells us
what this research can reveal about the causes of erectile
Dr. David Knowles:
There is a new study out of University of Tampere in Finland
that came to the conclusion that Aspirin and other
anti-inflammatory medications are related to erectile dysfunction
(ED). This has made some people come to the assumption that these
medications may cause ED. This is NOT the case. This study was not
designed to determine a cause and effect. They simply collected
data to see if there were any associations. They found an
association between people who take these medications and ED. If
you think about this it makes great sense. The two most common
reasons to take aspirin and other anti-inflam...
All drugs come with benefits and possible side effects or adverse events. For anyone suffering joint pain from osteoarthritis, nonsteroidal antiinflammatory drugs are often used to reduce pain from inflammation and improve function. But since osteoarthritis is a chronic condition, that can mean taking these medications for a very long time. And that increases the risk of problems or complications. One way around this is with the use of topical (lotions or gels applied to the skin) NSAID formulations. The results of this study show that one topical NSAID in particular may be helpful for those people who have mild to moderate knee arthritis. Diclofenac in a topical form was compared with oral diclofenac and with a placebo (pretend) topical solution. Over 700 patients with bilateral knee osteoarthritis were included in the study. Bilateral means both knees were affected. The diagnosis was confirmed with X-rays. They were divided into five groups. One group received treatment with topical d...
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