I take Warfarin, Cymbalta, Aciphex, Klonapin, Lipitor, Propranol (for headaches), Baclofen. I need something that will stop the nausea and vomiting and not interfere with my other meds.
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Q: I am a 51 year old female, post menopausal. I am taking Fioricet that doesn't help with the nausea.
Answers (2)
1/ 2/10 2:11pm
Gran,
-:¦:-•:*'""*:•.-:¦:-•*Welcome to MyMigraineConnection!*•-:¦:-•:*'""*:•.-:¦:-
There are both medications and "natural" remedies that you can use for nausea. Some people find that peppermint or ginger -- tea, candy, or just the smell -- will help with the nausea. Others of us take prescription medications for nausea. These include Compazine, Phenergan, and Reglan. Your doctor can advise you as to which would be best for you.
I'm curious about the Fioricet. Have you tried any of the Migraine abortive medications -- triptans, ergotamines, or Epidrin? They work to actually stop the Migrainous process in the brain, and that stops the symptoms, usually including the nausea. Pain medications such as Fioricet are usually prescribed as rescue medications to be taken when abortive medications fail. You can read more in Preventive, Abortive, and Rescue Medications - What's the Difference?.
I hope this helps.
Welcome again,
Teri
1/ 2/10 5:30pm
Gran,
The warnings about triptans such as Imitrex and antidepressants such as Cymbalta don't say they can't be taken together. They say that patients should be aware of symptoms that could indicate a problem and report them to their doctors. The issue is serotonin syndrome, which is very rare. You can read about that in Antidepressants, Triptans, and Serotonin Syndrome. There are now seven drugs in that class. You might talk with your doctor about these drugs and maybe ask for some samples.
Keep me posted?
Teri
1/ 2/10 6:12pm
Teri, I was in the George Washington hospital in DC back in early October for removal of a diseased kidney. I had one of the worst migraines I have ever had there. The pharmacist refused to give the Imitrix because I was taking Cymbalta. I'm sitting on the edge of the bed puking my guts out with my sunglasses on, and the nurse says I can give you Tylenol. I told them Tylenol does nothing by itself, so they gave me a shot of Demerol and a shot for the nausea. Finally relief was coming. Put my eye mask on and slept for a few hours. Thank goodness for a good pair of sunglasses, good drugs.
Gran
1/ 2/10 6:21pm
Gran,
Of course, this is a decision each of us needs to make after discussion with our doctors. I've taken triptans and an SSRI or SNRI antidepresant for many years with no problems.
I'm not trying to convince you of anything -- just to give you the available information so you're making informed choices. To that end, here's what's in the Imitrex prescribing info:
Serotonin Syndrome: The development of a potentially life-threatening serotonin syndrome may occur with triptans, including treatment with IMITREX, particularly during combined use with selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs). If concomitant treatment with sumatriptan and an SSRI (e.g., fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram) or SNRI (e.g., venlafaxine, duloxetine) is clinically warranted, careful observation of the patient is advised, particularly during treatment initiation and dose increases. Serotonin syndrome symptoms may include mental status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular aberrations (e.g., hyperreflexia, incoordination), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea).
It's not easy, is it?
Teri
1/ 2/10 6:40pm
Who should I be talking to, my Neurologist or my Primary Physician? I took Imitrex while I was taking Prozac with no problems 15 years ago.
1/ 2/10 6:47pm
Who prescribes your Migraine meds? Your antidepressant? The best person to talk to, I would think, is the doctor who prescribes your Migraine meds. If a different doctor prescribes your antidepressant, they might want to consult.
Teri
1/ 6/10 10:42pm
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By Gran— Last Modified: 12/26/10, First Published: 12/30/09
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Teri, I used to use Imitrex, but can't use it now because it reacts with Anti depressents Cymbalta. I tried Amerge years ago and it did not help. I have used Hydrozine in the past and that worked well, but if I can find something that would make the pain and nausea go away in one pill that would be better. I take so many drugs already and because of the Warfarin (blood thinner for clots) I can't take anything with aspirin in it. I will read about the 'Preventive, Abortive, and Rescue Medications.