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I have been on Topamax for 2 years and it did cut the frequency of my migraines in half!  Those bizarre side effects did go away at exactly the 6 week mark - just as my Dr. predicted .  I lost 8 lbs, but eventually they came back - that "side effect" is just not meant to last!  Be aware - the drug will more than likely make you cognitively slower and possibly tired at the end of the day.  (But you can reduce your dosage to find the balance you can live with.)  So, in the end, if you are debilitated with migraines, I would recommend Topamax.  My Dr. has taken me off it b/c I was down to 25 mg a day and I am starting to have more frequent migraines.  I am not willing to up my dosage - so we are trying "Migravent" as an alternative.  I am glad b/c I would much rather be on a natural-type remedy than a heavy duty RX drug.  I am keeping my fingers crossed.