What do you mean? Can you take advil and excedrin together? No, it's not a good idea to take them together because Advil (ibuprofen) is a nonsteriodal anti-inflammatory drug pain reliever and Excedrin is also a pain reliever that contains acetaminophen, aspirin and caffeine. These two drugs taken together have what's called a major drug interaction, something to do with aspirin and ibuprofen and blood clotting issues.
There is good news, there are now over 100 medications and supplements that can be used for Migraine and headache prevention. The frustration of trying to find what works for us can make it seem as if we've tried it all, but with so many possible preventives, it's literally impossible to have tried them all. See Migraine preventive medications - too many options to give up! for more information.
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